Mos limits the number of meiotic divisions in urochordate eggs

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Mos limits the number of meiotic divisions in urochordate eggs.

Mos kinase is a universal mediator of oocyte meiotic maturation and is produced during oogenesis and destroyed after fertilization. The hallmark of maternal meiosis is that two successive M phases (meiosis I and II) drive two rounds of asymmetric cell division (ACD). However, how the egg limits the number of meioses to just two, thereby preventing gross aneuploidy, is poorly characterized. Here...

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Mos in the Oocyte: How to Use MAPK Independently of Growth Factors and Transcription to Control Meiotic Divisions

In many cell types, the mitogen-activated protein kinase (MAPK) also named extracellular signal-regulated kinase (ERK) is activated in response to a variety of extracellular growth factor-receptor interactions and leads to the transcriptional activation of immediate early genes, hereby influencing a number of tissue-specific biological activities, as cell proliferation, survival and differentia...

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Number of Nuclear Divisions

The cell number of the early Drosophila embryo is determined by exactly 13 rounds of synchronous nuclear divisions, allowing cellularization and formation of the embryonic epithelium [1]. The pause in G2 in cycle 14 is controlled by multiple pathways, such as activation of DNA repair checkpoint, progression through S phase, and inhibitory phosphorylation of Cdk1, involving the genes grapes, mei...

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Meeting on Meiotic Divisions and Checkpoints

Introduction Meiosis is a special type of cell division through which haploid gametes are generated from diploid parent cells. This is accomplished by a first division that induces homologous chromosome segregation followed by a second mitosis-like division that promotes sister chromatid separation. During the prophase of meiosis I, three basic events take place: pairing of homologous chromosom...

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Prediction of the Weight and Number of Eggs in Mazandaran Native Fowl Using Artificial Neural Network

Traditional poultry production has changed to a considerable industry after few decades. Now, poultry industry is one of the main sectors to obtain the required protein for human consumption. Prediction of the weight and number of eggs according to economic traits can improve the efficiency of production and the profit of producers. In present study, the weight and number of eggs in Mazandaran ...

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ژورنال

عنوان ژورنال: Development

سال: 2011

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.057133